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Year : 1984  |  Volume : 16  |  Issue : 3  |  Page : 153--157

Biochemical and hematological effects of tolmetin, a new nonsteriodal anti-inflammatory drug

N Sangal1, BB Nayak2, VV Sharma3, MB Mishra4, VK Kulshrestha5 
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Correspondence Address:
N Sangal


1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,«SQ» serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.


How to cite this article:
Sangal N, Nayak B B, Sharma V V, Mishra M B, Kulshrestha V K. Biochemical and hematological effects of tolmetin, a new nonsteriodal anti-inflammatory drug.Indian J Pharmacol 1984;16:153-157


How to cite this URL:
Sangal N, Nayak B B, Sharma V V, Mishra M B, Kulshrestha V K. Biochemical and hematological effects of tolmetin, a new nonsteriodal anti-inflammatory drug. Indian J Pharmacol [serial online] 1984 [cited 2020 Mar 30 ];16:153-157
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1984;volume=16;issue=3;spage=153;epage=157;aulast=Sangal;type=0