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Year : 1982  |  Volume : 14  |  Issue : 4  |  Page : 309--312

Metoclopramide in tardive dyskinesia

TJ Hemnani1, PG Dashputra2, RN Sarda3 
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Correspondence Address:
T J Hemnani


The effect of single intravenous doses of metoclopramide ( 10 mg, 20 mg and 40 mg) have been compared with placebo (saline) in a double blind randomised study in 10 patients with tardive dyskinesia, following long term neurokptic therapy. Tardive dyskinesia rating scores were decreased significantly 6 h after administration of meloclopramide (20 mg and 40 mg), when compared with placebo. Reduction of tardive dyskinasia by metoclopramide. ,aD2 receptor- blocking agent, suggest that D2 receptors may be involved in the mediation of this syndrome.


How to cite this article:
Hemnani T J, Dashputra P G, Sarda R N. Metoclopramide in tardive dyskinesia.Indian J Pharmacol 1982;14:309-312


How to cite this URL:
Hemnani T J, Dashputra P G, Sarda R N. Metoclopramide in tardive dyskinesia. Indian J Pharmacol [serial online] 1982 [cited 2020 Apr 8 ];14:309-312
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1982;volume=14;issue=4;spage=309;epage=312;aulast=Hemnani;type=0