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Year : 1982  |  Volume : 14  |  Issue : 4  |  Page : 293--299

Comparison of antidiarrhoeal activity of some drugs in experimental diarrhoea

Yegnanarayan Radha1, DS Shrotri2 
1 
2 

Correspondence Address:
Yegnanarayan Radha


A number of antidiarrhoeal agents were tried in experimental models of diarrhoea viz., castor oil-induced diarrhoea in rats, serotonin-induced diarrhoea in mice, and cholera toxin hypersecretion in rats. The agents, lidamidine. diphenoxylate+atropine. furazolidine, berberine and belladonna were given as pretreatment before the diarrhoea1 challenge, either singly or in various combinations. Lidamidine was most effective among the agents studied.Combinations except for those with lidamidine, offered no additional advantage over single drugs.


How to cite this article:
Radha Y, Shrotri D S. Comparison of antidiarrhoeal activity of some drugs in experimental diarrhoea.Indian J Pharmacol 1982;14:293-299


How to cite this URL:
Radha Y, Shrotri D S. Comparison of antidiarrhoeal activity of some drugs in experimental diarrhoea. Indian J Pharmacol [serial online] 1982 [cited 2020 Jun 5 ];14:293-299
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1982;volume=14;issue=4;spage=293;epage=299;aulast=Radha;type=0