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|Year : 1982 | Volume
| Issue : 3 | Page : 229--232
Effect of pyrantel pamoate on the development of hook-worm
KC Singhal1, RR Gupta2, PN Saxena3, Kumar Anil4
Pyrantel pamoate. a broad spectrum anthelmintic, was investigated for its effect on the developmental stages of sheep hook worm, Haemonchus controlus.
Addition of pyrantel pamoate to the faeces charcoal mixture caused concentration-related inhibition of transformation of Haemonchus contorlus seggs to infective larvae, the LC50 and LC90 being 54.95 ñ 6.90 and 400.00 ñ 49.10 mcg, respectively. On infective larvae, pyrantel pamoate produced contracture and decrease in motility leading to irreversible. paralysis.
K C Singhal
|How to cite this article:|
Singhal K C, Gupta R R, Saxena P N, Anil K. Effect of pyrantel pamoate on the development of hook-worm.Indian J Pharmacol 1982;14:229-232
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Singhal K C, Gupta R R, Saxena P N, Anil K. Effect of pyrantel pamoate on the development of hook-worm. Indian J Pharmacol [serial online] 1982 [cited 2020 Apr 6 ];14:229-232
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1982;volume=14;issue=3;spage=229;epage=232;aulast=Singhal;type=0