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Year : 1982  |  Volume : 14  |  Issue : 3  |  Page : 229--232

Effect of pyrantel pamoate on the development of hook-worm

KC Singhal1, RR Gupta2, PN Saxena3, Kumar Anil4 
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Correspondence Address:
K C Singhal


Pyrantel pamoate. a broad spectrum anthelmintic, was investigated for its effect on the developmental stages of sheep hook worm, Haemonchus controlus. Addition of pyrantel pamoate to the faeces charcoal mixture caused concentration-related inhibition of transformation of Haemonchus contorlus seggs to infective larvae, the LC50 and LC90 being 54.95 6.90 and 400.00 49.10 mcg, respectively. On infective larvae, pyrantel pamoate produced contracture and decrease in motility leading to irreversible. paralysis.


How to cite this article:
Singhal K C, Gupta R R, Saxena P N, Anil K. Effect of pyrantel pamoate on the development of hook-worm.Indian J Pharmacol 1982;14:229-232


How to cite this URL:
Singhal K C, Gupta R R, Saxena P N, Anil K. Effect of pyrantel pamoate on the development of hook-worm. Indian J Pharmacol [serial online] 1982 [cited 2020 Apr 6 ];14:229-232
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1982;volume=14;issue=3;spage=229;epage=232;aulast=Singhal;type=0