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Year : 1978  |  Volume : 10  |  Issue : 3  |  Page : 239--241

Hypoglycaemic effect of combination of glibenclamide and phenformin- an experimental study

V Mohan1, SK Nazimudeen2, M Vishwanathan3, L Kameswaran4 
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Correspondence Address:
V Mohan


. Clinical studies have shown that a combination of glybenclamide and phenformin is more useful in control of diabetes than either drug used alone. This pharmacological study shows that phenformin had no significant hypoglycaemic effect in normal dogs. However, when phenformin is combined with glybenclamide, the effect was more marked and quicker than with glybenclamide alone. The different sites of action of the drugs may be responsible for this interesting response.


How to cite this article:
Mohan V, Nazimudeen S K, Vishwanathan M, Kameswaran L. Hypoglycaemic effect of combination of glibenclamide and phenformin- an experimental study.Indian J Pharmacol 1978;10:239-241


How to cite this URL:
Mohan V, Nazimudeen S K, Vishwanathan M, Kameswaran L. Hypoglycaemic effect of combination of glibenclamide and phenformin- an experimental study. Indian J Pharmacol [serial online] 1978 [cited 2019 Oct 21 ];10:239-241
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1978;volume=10;issue=3;spage=239;epage=241;aulast=Mohan;type=0