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 SHORT COMMUNICATION
Year : 2016  |  Volume : 48  |  Issue : 2  |  Page : 214-215

The effect of methanolic extract of Buchanania lanzan Spreng seeds on hematological indices


Department of Pharmacology and Toxicology, B. R. Nahata College of Pharmacy, Mandsaur, Madhya Pradesh, India

Correspondence Address:
Mandeep Kumar Singh
Department of Pharmacology and Toxicology, B. R. Nahata College of Pharmacy, Mandsaur, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7613.178835

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Objective: The objective of the current study was carried out to investigate the effects of methanolic extract of Buchanania lanzan Spreng seeds on hematological indices. Materials and Methods: Eighteen male albino Wistar rats were divided into three groups, six in each. Group I animals received distilled water, Group II and III were treated with an oral dose of 1000 mg oil/kg and 2000 mg oil/kg of extract, respectively, for 7 days. At the end of the study, blood was collected and evaluated for packed cell volume (PCV), hemoglobin (Hb) concentration, and red blood cell (RBC) and white blood cell (WBC) counts. Results: There was a significant dose-dependent increase in the hematological indices such as PCV, Hb, RBC, and WBC count in the treatment group. Conclusions: The improvement of PCV, Hb, and RBC values is an indication of the anti-anemic effect which may be due to the stimulation of RBC production in bone marrow. Further, stimulated production of WBC could be as a result of possible stimulus of the immune system. Hence, this study confirms that the extract of B. lanzan could be useful for the treatment of anemia.






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