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 DRUG WATCH
Year : 2014  |  Volume : 46  |  Issue : 6  |  Page : 653-654

Linezolid induced black hairy tongue


1 Department of Dermato-Venereology, Government Mohan Kumaramangalam Medical College Hospital, Salem, Tamil Nadu, India
2 Department of Pharmacology, Annapoorana Medical College and Hospitals, Salem, Tamil Nadu, India
3 Department of Dermato Venereology, Government Mohan Kumaramangalam Medical College Hospital, Salem, Tamil Nadu, India
4 Department of Orthopedics, Government Mohan Kumaramangalam Medical College Hospital, Salem, Tamil Nadu, India

Correspondence Address:
B Maharani
Department of Pharmacology, Annapoorana Medical College and Hospitals, Salem, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7613.144942

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Black hairy tongue (BHT) also called as lingua villosa nigra, is a self limiting benign condition characterized by hypertrophy and elongation of filiform papillae of tongue with brown or black discoloration. Smoking, poor oral hygiene, xerostomia, using peroxide containing mouth washes, substance abuse and drugs (steroids, methyldopa, olanzapine, etc) are the predisposing factors. However its occurrence in relation to linezolid ingestion among south Indians has not been reported in PubMed database. Here we report a case, where significant association of linezolid intake with BHT was found in a 10-year-old boy, who was treated with tablet linezolid for post surgical infection of left side radial neck fracture. This case is reported for the rarity of occurrence with linezolid therapy. According to Naranjo adverse drug reaction (ADR) causality scale, the association of BHT due to linezolid in our case was probable.






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