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 DRUG WATCH
Year : 2013  |  Volume : 45  |  Issue : 4  |  Page : 410-411

Inflamed psoriatic plaques: Drug toxicity or disease exacerbation?


1 Department of Dermatology and Venereology, Pt BDS PGIMS, Rohtak, Haryana, India
2 Department of Pharmacology, Pt BDS PGIMS, Rohtak, Haryana, India

Correspondence Address:
Nidhi Jindal
Department of Dermatology and Venereology, Pt BDS PGIMS, Rohtak, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7613.115001

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We are presenting a case of Methotrexate treated stable plaque psoriasis, in whom inflamed psoriatic plaques of drug toxicity were misdiagnosed as disease exacerbation. Erosive psoriatic plaques were present in the absence of biochemical or hematological derangements. Ulceration of psoriatic plaques in the presence of disturbed hematological profile is well described as a harbinger of methotrexate toxicity, but this kind of erosions in the absence of any systemic involvement is the first report of its kind.






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