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 DRUG WATCH
Year : 2010  |  Volume : 42  |  Issue : 6  |  Page : 416-417

Acute akathisia with quetiapine: A case report and review of literature


Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India

Correspondence Address:
Sandeep Grover
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7613.71896

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Quetiapine is an atypical antipsychotic which has been shown to have greater relative affinity for 5-HT 2A receptors than for D 2 receptors, due to which it is thought to lead to lower incidence of extrapyramidal symptoms (EPS). However, over the years literature in the form of case reports have accumulated which shows that quetiapine can lead to akathisia, especially in subjects prone to develop EPS. In this study, we report the case of a 22-year-old female who developed akathisia with quetiapine 150 mg/day, which subsided with reduction in dose. We have also reviewed the existing literature with respect to akathisia with quetiapine.






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