IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1757 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3580    
    Printed120    
    Emailed1    
    PDF Downloaded281    
    Comments [Add]    
    Cited by others 3    

Recommend this journal

 

 RESEARCH ARTICLE
Year : 2010  |  Volume : 42  |  Issue : 5  |  Page : 297-300

Antimicrobial consumption and impact of "Reserve antibiotic indent form" in an intensive care unit


1 Deparment of Clinical Pharmacology, Super Religare Laboratories, Fortis FLT LT Rajan Dhall Hospital, Vasant Kunj, New Delhi, India
2 Department of Microbiology, Super Religare Laboratories, Fortis FLT LT Rajan Dhall Hospital, Vasant Kunj, New Delhi, India

Correspondence Address:
Purabi Reang Sharma
Deparment of Clinical Pharmacology, Super Religare Laboratories, Fortis FLT LT Rajan Dhall Hospital, Vasant Kunj, New Delhi
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7613.70216

Rights and Permissions

Objective : To study the antimicrobial (AM) consumption, record the AM sensitivity pattern, and evaluate impact of "Reserve AM indent form" in the intensive care unit (ICU). Materials and Methods : The study was carried out in medical ICU over 4 months period at a tertiary care hospital. AM consumption was determined by defined daily dose (DDD) per 100 bed days for each month for consecutive 4 months. The average total AM consumption was calculated. The laboratory samples were processed, and the sensitivity pattern was determined. Some of the newer AM were categorised as "Reserve" and an indent form was made mandatory to be filled up prior to prescription. Results : The total AM consumption was 232 per 100 bed days. The commonly used AM were penicillin with b-lactamase inhibitor (21%) followed by antifungal drugs (13.4%), cephalosporins and macrolides (11.7%) each. The most common organism isolated was Acinetobacter (26.1%) followed by Candida (23.8%) and Pseudomonas (21.4%). The average occupancy index was 0.53, and the average duration of ICU stay was 6 days. The consumption of carbapenems (new AM) and antifungals decreased from 18.8/100 to 10.6/100 and 56.1/100 to 22.1/100 bed days, respectively, after the introduction of indent form. Conclusion : The "Reserve AM indent form" was helpful in reducing the AM consumption during the study period. The AM indent form can be used as an important tool to combat irrational use, AM resistance and can be implemented in AM stewardship programmes.






[FULL TEXT] [PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow