IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 696 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2756    
    Printed111    
    Emailed5    
    PDF Downloaded754    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 2000  |  Volume : 32  |  Issue : 6  |  Page : 357-360

Analgesic and antipyretic activities of Dalbergia sissoo leaves



Correspondence Address:
S W Hajare


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Objective: To evaluate the analgesic and antipyretic activities of alcoholic extract of Dalbergia sissoo leaves. Methods: The peripheral analgesic activity of Dalbergia sissoo leaves (SLE; 100, 300 and 1000 mg/kg) was studied using acetic acid induced writhing in mice and by Randall-Selitto assay. The central analgesic activity of SLE was studied using hot-plate method and tail clip test in mice. The antipyretic activity of SLE was studied in Brewer's yeast-induced pyrexia in rats. Results: SLE significantly decreased the writhing movements in mice in acetic acid-induced writhing test. SLE (1000 mg/kg) significantly increased the pain threshold capacity in rats in Randall-Selitto assay and the reaction time in hot-plate test but not in tail-clip test. It also showed significant antipyretic activity in Brewer's yeast-induced pyrexia in rats throughout the observation period of 6 h. Conclusion: SLE may have analgesic and antipyretic activities.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow