| RESEARCH PAPER
|Year : 2000 | Volume
| Issue : 5 | Page : 300-304
Aphrodisiac activity of Vanda tessellata (Roxb.) Hook.Ex Don extract in male mice
Kumar PK Suresh, A Subramoniam, P Pushpangadan
Objective: To study the effect of V. tessellata on the sexual behaviour of male mice and general toxicity, if any, in mice.
Methods: An aqueous suspension (2 g/kg, wet wt.) or extract (water or alcohol, 200 mg/kg) of root, flower or leaf of V. tessellata was administered ( p.o.) to male mice and 1 hr, after administration their mounting behaviour was observed. The most active extract (alcohol extract of flower) was administered (50 or 200 mg/kg, p.o.) to different groups of male mice and their mounting behaviour, mating performance and reproductive performance were determined. The general short term toxicity of the alcohol extract in male mice was also determined.
Results: The flower and, to some extent, the root, but not the leaf of V. tessellata was found to stimulate the mounting behaviour of male mice. This activity was found in the alcohol extract of the flower. This extract (50 or 200 mg/kg) also increased mating performance in the mice. The pups fathered by the extract treated mice were found to be normal with an increasing trend in the male/female ratio of these pups. The alcohol extract was devoid of any conspicuous general toxicity.
Conclusion: The alcohol extract of V. tessellata flower stimulates the sexual behaviour of male mice.
Kumar PK Suresh
Source of Support: None, Conflict of Interest: None