| RESEARCH PAPER
|Year : 2000 | Volume
| Issue : 1 | Page : 7-10
Effect of DLH-721A and DLH-721B (polyherbal formulations) on rat mesenteric mast cell degranulation
K Padmalatha, BV Venkataraman, R Roopa
Objective: To study the antianaphylactic effect of DLH-721A and DLH-721B (herbal formulation) on the rat mesenteric mast cells.
Methods: The study was carried out on the rat mesenteries sensitised with sheep serum to induce mast cell degranulation. Mesenteries pretreated with prednisolone, disodium cromoglycate, DLH-721A and DLH-721B were analysed for the mast cell degranulation during the anaphylactic reactions.
Results: Treatment with DLH-721A and DLH-721B showed beneficial effect on degranulation of actively and passively sensitised mesenteric mast cells. The protective effect was comparable with that of prednisolone and disodium cromoglycate.
Conclusion: DLH-721A and DLH-721B may have antianaphylactic activity on the rat mesenteric mast cells.
Source of Support: None, Conflict of Interest: None