| SHORT COMMUNICATION
|Year : 1999 | Volume
| Issue : 3 | Page : 229-231
Effect of gentamicin on specific immune response in rabbits
HB Asha, gowda Honne, K Narayana, G Krishnappa, K Jayakumar
Objective: To study the effect of gentamicin on humoral and cell mediated immune system in rabbits.
Methods: Rabbits were treated with gentamicin at 4 mg/kg and 8mg/kg body weight doses for 5 days along with single intramuscular injection of 0.5 ml of Brucella plain killed antigen and humoral and cellular immune responses were measured.
Results: There was no significant variation in the humoral and cellular immune response between the antigen control and the groups given gentamicin along with antigen.
Conclusion: Gentamicin at the two dose levels used for 5 days, in rabbits, did not affect the specific immune response.
H B Asha
Source of Support: None, Conflict of Interest: None