| RESEARCH PAPER
|Year : 1999 | Volume
| Issue : 2 | Page : 124-127
The effect of panax ginseng and diazepam on norepinephrine levels of whole brain and hypothalamus during stress
D Bhattacharyya, TK Sur
Objective: To see the effect of anti-stress agents like Panax ginseng and diazepam on stress-induced elevation of norepinephrine (NE) in brain and hypothalamus of rats.
Methods: NE was estimated in brain and hypothalamus of rats by spectrophotofluorimetry. Plasma corticosterone was measured by fluorimetry.
Results: Panax ginseng and diazepam both per se did not modify NE levels of brain and hypothalamus in unstressed rats. But both the drugs attenuated stress-induced elevation of NE of brain and hypothalamus and simultaneously attenuated stress-induced elevation of plasma corticosterone.
Conclusion: Anti-stress effect of Panax ginseng and diazepam seems to be mediated through attenuation of levels of NE in brain and hypothalamus.
Source of Support: None, Conflict of Interest: None