IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1089 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1344    
    Printed85    
    Emailed1    
    PDF Downloaded251    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1998  |  Volume : 30  |  Issue : 3  |  Page : 163-168

lmmunopotentiating and immunoprophylactic activities of lmmue 21, a polyherbal product



Correspondence Address:
D e Pallabi


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Objective: To evaluate the immunopotentiating and immunoprophylactic effects of Immue-21 (l-21) a polyherbal Ayurvedic product. Methods: Effect of l-21 (50 mg/kg, p.o), on morphometric and functional changes of mouse peritoneal macrophage was evaluated. Its effect on chemotaxis assay for leucocytes and on heamatological parameters were also studied. Adjuvant effect of l-21 was studied in rabbits. lmmunopotenttating effect of l-21 was studied against UV rays,cyclophosphamide and cyclosporine induced immunosuppression in mice and rats. lmmunoprophylactic effect of l-21 was studied in E.coli induced peritonitis in mice. Results: l-21 exhibited a significant increase in both morphometric and functional changes of macrophage in mice. It also significantly increased in vitro chemotaxis of leucocytes and in vivo total WBC and RBC counts in albino mice. l-21 significantly potentiated humoral immunity in rabbits and showed significant protection against UV rays, cyclophosphamide and cyclosporine A induced immunosuppression. l-21 provided 50% protection against E. coli induced abdominal peritonitis in albino mice. Conclusion: l-21 may have immunopotentiattng and immunoprophylactfc activity.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow