IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1131 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1263    
    Printed75    
    Emailed0    
    PDF Downloaded121    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1998  |  Volume : 30  |  Issue : 3  |  Page : 152-162

Role of S-Allyl cysteine sulphoxide in antagonizing deleterious metabolic effects of monosodium glutamate in rats on atherogenic diet



Correspondence Address:
K N Bopanna


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

0bjective:To study the effect of S-allyl cysteine sulphoxide (SACS) in antagonising deleterious metabolic effects of monosodium glutamate in rats on atherogenic diet. Methods: Rats on atherogenic diet with monosodium glutamate at two doses received SACS for thirty days. At the end of thirty days, blood pressure, heart rate, serum lipid levels and activities of some serum, liver, heart and intestinal enzymes were assessed. Results: SACS significantly decreased the concentration of serum lipids except HDL cholesterol and enzyme activities in serum, liver, heart and intestine in rats treated with MSG at both doses. There was no significant effect of SACS on phosphatases in rats treated with MSG (1 g/kg). SACS did not have any significant effect on blood pressure and heart rate. SACS significantly decreased pentobarbitone induced sleeping time in rats on MSG with atherogenic diet. Conclusions: Our data suggests that SACS significantly antagonises the metabolic aberrations caused by MSG in rats on atherogenic diet.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow