IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1775 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1592    
    Printed86    
    Emailed0    
    PDF Downloaded185    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1998  |  Volume : 30  |  Issue : 2  |  Page : 68-72

Toad (Bufo Melanostictus, Schneider) skin extract induced haematological and biochemical changes in rodents



Correspondence Address:
Das Manika


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

0bjective:To examine the haematological and biological changes induced by the toad skin extract (TSE) of the common Indian toad (Bufo melanostictus) in rodents. Methods:TSE was injected (SC) in male albino mice and rat (normal and splenectomized) and haemoglobin, haematocrit, RBC and WBC counts were done at different time intervals. Serum glucose, cholesterol, HDL-cholesterol, triglycerides, urea creatinine, iron, total iron binding capacity (TIBC), transaminase and phosphatase levels were also measured on TSE injected male albino rats. Results: TSE significantly decreased haemoglobin, haematocrit and total RBC count of male albino mice. However, it significantly increased total WBC, lymphocyte and monocyte count. In splenectomized rat, TSE showed no change on haemoglobin, haematocrit and total RBC count but increased total WBC and lymphocyte count. TSE also produced significant fall of serum glucose, cholesterol, triglyceride, urea and transminase levels and increased serum iron and TIBC level in male albino rats. Conclusion:TSE induced changes on haematological and biochemical parameters in rodents, indicated the toxic nature of TSE.This toxicity of TSE probably provides first line of defence in toad against predators.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow