IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 3189 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1798    
    Printed90    
    Emailed2    
    PDF Downloaded264    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1997  |  Volume : 29  |  Issue : 4  |  Page : 255-257

Action of garlic on the hyperlipidemia of experimental induced immune complex disease in rabbits



Correspondence Address:
R C Jain


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Objective: To study the effect of garlic on hyperlipidemia in immune complex disease in rabbits. Methods: Experimental induced immune complex disease was produced in 22 albino male rabbits (1.0-l .5 kg) by injecting horse serum proteins at a dose of 175 mg/kg body weight, every 72 hours i.v., and divided into two groups. Twelve rabbits were treated with 75 mg/kg body weight garlic oil orally daily and served as test group. Ten rabbits without supplementation of garlic oil served as control group. The observation period was 4 weeks. Results: Serum complement titre was significantly decreased in test group as compared to control group (19.50(1.5 vs 2.O(0.5; P<0.001) at the end of 4th week. The total lipids, total cholesterol and beta lipoprotein cholesterol were significantly lower in test group, when compared to control groups, However, levels of triglycerides and phospholipids in test group were not significant when compared to control. Conclusion: It is observed that garlic possesses anticomplementary and hypolipidemic activity in hyperlipidemia due to induced Immune complex disease.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow