IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1475 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2942    
    Printed135    
    Emailed5    
    PDF Downloaded454    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1996  |  Volume : 28  |  Issue : 3  |  Page : 161-166

Effect of Plumbago zeylanica in hyperlipidaemic rabbits and its modification by vitamin E


Correspondence Address:
Ram Alpana


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Effect of ethanolic extract (50% v/v) of Plumbago zeylanica (root) alone and combined with vitamin E (an antioxidant)was studied in experimentally induced hyperlipidaemic rabbits. There was significant reduction in serum total cholesterol, LDL cholesterol and triglyceride levels. Marked reduction was observed with the formulation of P.zeylanica and vitamin E. The total cholesterol/HDL and LDL/HDL cholesterol ratios were found significantly decreased (P<0.05). P.zeylanica showed good margin of safety as determined by acute toxicity studies in albino rats and albino rabbits, as well as by the absence of adverse effects on haematological and biochemical parameters in albino rabbits upto 60 days of administration.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow