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 SHORT COMMUNICATION
Year : 1995  |  Volume : 27  |  Issue : 4  |  Page : 258-261

Estrogenic activity in the ethanolic extract of Bupleurum marginatum



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Jonathan Sheel


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Ethanolic extract of Bupleurum marginafum (Sipil) having potent antifertility activity in rats has been studied to assess its estrogenic activity in immature rats. It has been observed that administration of extract per se significantly increased the uterine weight and caused opening and cornification of vagina in immature rats. Histological features of uterus were seen to be highly stimulated. Uterotrophic activity of the extract has been compared with diethylstilbestrol, a standard estrogenic agent.






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