| SHORT COMMUNICATION
|Year : 1995 | Volume
| Issue : 2 | Page : 127-129
Preferred anaesthetic agents in experimental cardiology: a study on rat electrocardiogram
Kumar Sanjay, AK Kela, VL Mehta, AK Shukla
Different anaesthetic agents are used to record the rat electrocardiogram which is a commonly used parameter for various pharmacological and toxicological studies. In the present study, light ether anaesthesia was administered to the control group and the effects of other commonly used anaesthetic agents were compared with that of control group. It was observed that light ether and pentobarbitone anaesthesia produced minimal cardiac effects whereas urethane, chloralose, moderate and deep ether anaesthesia produced significant fall in heart rate and other cardiac toxicities. Hence, light ether anaesthesia is advisable to be used in acute experiments of short duration and pentobarbitone where anaesthesia of long duration is desired while recording rat electrocardiogram.
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