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 SHORT COMMUNICATION
Year : 1994  |  Volume : 26  |  Issue : 4  |  Page : 304-306

Lack of genotoxicity of omeprazole in chromosomal aberration and sisterChromatid exchange assays using cultured human lymphocytes in vitro



Correspondence Address:
T S Kumaravel


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Omeprazole was tested in chromosomal aberration (CA) and sister chromatid exchange (SCE) assays using cultured human lymphocytes in vitro. While CA is a standard battery of test system in mutagenicity studies, SCE is considered to be the most simple reliable and sensitive index of DNA damage/repair. Omeprazole was found to be non toxic in both these tests.






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