| SHORT COMMUNICATION
|Year : 1994 | Volume
| Issue : 4 | Page : 304-306
Lack of genotoxicity of omeprazole in chromosomal aberration and sisterChromatid exchange assays using cultured human lymphocytes in vitro
TS Kumaravel, Lakshmi Karthika, P Balakrishnamurthy
Omeprazole was tested in chromosomal aberration (CA) and sister chromatid exchange (SCE) assays using cultured human lymphocytes in vitro. While CA is a standard battery of test system in mutagenicity studies, SCE is considered to be the most simple reliable and sensitive index of DNA damage/repair. Omeprazole was found to be non toxic in both these tests.
T S Kumaravel
Source of Support: None, Conflict of Interest: None