IPSIndian Journal of Pharmacology
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Year : 1993  |  Volume : 25  |  Issue : 4  |  Page : 252-253

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1. The effect of ambient temperature (Ta) on rectal temperature (Tr) of rats during rest and physical exercise and of antipyretics on exercise-induced hyperthermia in rats and rabbits has been investigated. 2. Body temperature increases with increase in Ta. 3. Physical exercise increases body temperature and the thermal equilibrium reached is proportional to exercise. Increase in Ta causes greater hyperthermia during exercise. 4. The exercise hyperthermia is not due to an elevation in body temperature set-point as aspirin and indomethacin do not block exercise-induced hyperthermia as they do the pyrogen fever. 5. The rise in body temperature is the limiting factor for the continuation of exercise.


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