IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1374 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1099    
    Printed73    
    Emailed2    
    PDF Downloaded156    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1993  |  Volume : 25  |  Issue : 4  |  Page : 209-214

Studies on the antihypertensive effect of abana in rats



Correspondence Address:
R Balaraman


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Treatment with Abana (3 g/kg/day, p.o) for 3 weeks, reduced the blood pressure of unilaterally nephrectomized DOCAsalt-treated hypertensive rats. Similar reduction in blood pressure was also observed in the CdCl2 (1 mg/kg/day, i.p. for two weeks) treated hypertensive rats. The pressor response to adrenaline and noradrenaline (1 and 2 'g/kg) was reduced by chronic administration of Abana in these hypertensive animals. However, Abana (3 g/kg/day, p.o) administered to normotensive female albino rats for 3 weeks did not alter the mean blood pressure and the pressor response to adrenaline and noradrenaline (1 and 2 'g/kg). The vascular reactivity to noradrenaline in isolated aortic strip and portal vein was also reduced by the chronic administration of Abana in the hypertensive rats. It is concluded that the antihypertensive effect of Abana might be due to its alteration of cation transport into the cell.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow