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 REVIEW ARTICLE
Year : 1993  |  Volume : 25  |  Issue : 4  |  Page : 193-198

Measurement of physiologic parameters from isolated perfused rat heart by a computerised system



Correspondence Address:
B V Venkataraman


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This report details a field study of a computer-based system for the recording of physiologic parameters with descriptive records of calibration, storage, and printout of waveform data obtained from an isolated rat heart preparation. Conventional analogue data of developed tension and left ventricular pressure were recorded, respectively, by using a strain gauge and pressure transducer coupled to a multi-channel, strip chart recorder. Simultaneously, the preamplified polygraph signals were linked to a CODAS analogue to digital conversion system and an IBM compatible laptop computer for continuous data acquisition. Because this CODAS preamplification system is equipped with a built-in excitation capability, the system has also been used to process analogue signals directly from a strain gauge and a pressure transducer independent of a multi-channel electromechanical recorder. The superior storage and data acquisition, playback, signal derivitization and statistical analysis capabilities of the computer-based system are discussed. In addition, since this portable computer-based analogue to digital recording system can function independently of a costly preamplification system such as the traditional multichannel chart recorders, because it contains built-in transducer excitation means, this system has potential cost saving and data processing advantages for use in applications where budgetary constrains are paramount.






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