| RESEARCH PAPER
|Year : 1991 | Volume
| Issue : 3 | Page : 137-142
Effect of anti-stress plants on biochemical changes during stress reaction
N Singh, N Misra, AK Srivastava, KS Dixit, GP Gupta
1. Effect of alcoholic extracts of plants, Eleutherococcus senticosus (Siberian plant) and Ocimum sanctum (Indian plant) described earlier as anti-stress agents was studied on the changes in central neurotransmitter (adrenaline, noradrenaline, dopamine, 5-hydroxytrypamine) levels and enzyme (monoamine oxidase) activity in the brain induced by stressors.
2. Two kinds of stressors were used, 5 hours swimming in mice and 2 hours gravitational stress in rats.
3. There was an increase in the levels of dopamine (DA) and 5-hydroxytryptamine (5-HT) and decrease in adrenaline (A) noradreneline (NA) and monoamine oxidase (MOA) in stressed animals.
4. Both anti-stress drugs prevented the decrease in A, NA, MAO and 5-HT. The increase in DA was facilitated.
5. Prevention and facilitation of changes in brain neurotransmitters and enzymes by anti-stress agents appear to enhance the stress-adaptation phenomenon for better coping of the organism during stressful situations.
Source of Support: None, Conflict of Interest: None