IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 3145 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1330    
    Printed78    
    Emailed0    
    PDF Downloaded111    
    Comments [Add]    

Recommend this journal

 

 RESEARCH PAPER
Year : 1985  |  Volume : 17  |  Issue : 4  |  Page : 192-196

Cardiovascular effects of central and peripheral administration of dopamine in hypertensive and normotensive rats



Correspondence Address:
JSL Mok


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

1. Effects of intracerebroventricular (i.c.v.) and intravenous (i.v.) injection of dopamine (DA), 12.5- 400 (g/kg on blood pressure (BP) and heart rate (HR) were studied in conscious spontaneously hypertensive rats (SHR) and compared with 2 other models of hypertension and their normotensive controls. 2. Blood pressure decreased significantly in SHR after i.c.v. DA when compared to hypertensive and normotensive controls in a dose-related manner. 3. HR decreased in all cases except that at a dose of more than 25(gDA/kg in SHR an increase was seen. 4. The results support the hypothesis for a central dopaminergic insufficiency in SHR.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow