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 SHORT COMMUNICATION
Year : 1985  |  Volume : 17  |  Issue : 3  |  Page : 173-175

Effects of antitubercular drugs on hexobarbitone sleeping time in mice



Correspondence Address:
G F Shah


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(1) The influence of various antitubercular drugs either alone or in combination on hexobarbitone metabolism was studied in mice by observing its sleeping time. (2) Ethambutol and pyrazinamide did not affect the hexobarbitone sleeping time. (3) isoniazid alone and in combination with pyrazinamide significantly increased, while rifampicin (7 days administration) alone and in combination with other antitubercular drugs used decreased hexobarbitone sleeping time.






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