| SHORT COMMUNICATION
|Year : 1985 | Volume
| Issue : 3 | Page : 173-175
Effects of antitubercular drugs on hexobarbitone sleeping time in mice
GF Shah, JD Raval, TP Gandhi, PR Patel, MR Patel
(1) The influence of various antitubercular drugs either alone or in combination on hexobarbitone metabolism was studied in mice by observing its sleeping time.
(2) Ethambutol and pyrazinamide did not affect the hexobarbitone sleeping time.
(3) isoniazid alone and in combination with pyrazinamide significantly increased, while rifampicin (7 days administration) alone and in combination with other antitubercular drugs used decreased hexobarbitone sleeping time.
G F Shah
Source of Support: None, Conflict of Interest: None