| RESEARCH PAPER
|Year : 1984 | Volume
| Issue : 3 | Page : 129-131
Effect of propranolol on aggressive behaviour in rats
A Ray, M Alkondon, P Sen
1. (Propranolol in doses of 1 and 3 mg/kg facilitated whereas 10 and 30 mg/kg inhibited footshock aggression (FSA) in rats.
2. Atropine but not atropine methylnitrate antagonised the antiaggressive effect of (() propranolol (IO mg/kg) wlthout affecting the facilitatory affect on FSA.
3. Racemic propranolol (1 and 10 mg/kg) also antagonised reserpine apomorphine aggression.
4. It is suggested that central cholinergic as well as dopaminergic mechanisms could be involved in the anti-aggressive effect of propranolol.
Source of Support: None, Conflict of Interest: None