| RESEARCH PAPER
|Year : 1980 | Volume
| Issue : 1 | Page : 19-22
A clinical trial with mebendazole in taeniasis saginata and Hymenolepis nana
KC Singhal, RA Khan, PN Saxena
Mebendazole, a broad spectrum anthehnintic was evaluated in 32 patients parasitized with tape worm infestations. Eighteen patients were identified as having Hymenolepis nana and 14 as having Taenia saginata. Seventeen patients in addition, were found to have concomitant nematode infection. Patients were treated with one of the five dosage schedules (100 mg b.d. x 3 days, 100 mg q.i.d. x 3 days, 300 mg b.d. x 1 day, 300 mg b.d. x 3 days and 500 mg b.d. x 1 day). Treatment resulted in the passage of long chains of proglottids of T. saginata and whole worms of H. nana. Assessment of results was made at 15 day intervals for 3 months. The most effective dosage schedule was 300 mg b.d. for 3 days which resulted in curing all the six patients suffering from T. saginata and 7 of the 10 harbouring H. nana.
K C Singhal
Source of Support: None, Conflict of Interest: None