IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 1209 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1516    
    Printed75    
    Emailed1    
    PDF Downloaded135    
    Comments [Add]    

Recommend this journal

 

 SHORT COMMUNICATION
Year : 1979  |  Volume : 11  |  Issue : 3  |  Page : 233-237

A note on the need for pyrogen test in aminophylline injection



Correspondence Address:
S C Gupta


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

. The test for freedom from pyrogens in aminophylline injection is not prescribed in any pharmacopoeia probably in the belief that theophylline contained in aminophylline injection, being a xanthine derivative, may interfere with the pyrogen test because of its antipyretic property. This investigation reveals that doses of aminophylline as high as 25 mg/kg do not interfere with the official test in rabbits and that when the sample was contaminated with a pyrogenic material, a rise in temperature was observed.The inclusion of the test for freedom from pyrogens in aminophylline injection in the official compendia is therefore recommended.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow