| RESEARCH PAPER
|Year : 1977 | Volume
| Issue : 3 | Page : 195-198
Screening of some antifungal agents against dermatophytes
SK Misra, KC Sahu
Preliminary screening of 8 chemicals was done for antifungal action in vitro against Trichophyton verrucosum, Tricho-phyton mentagrophytes and Trlchophyton simil Griseofulvin. Thiabendazole and organic chlorinated hydrocarbon (Sulfenimide) exhibited uniform antifungal action against all the three test dermatophytes. Chemicals like copper oxychloride, micronised wettable sulphur and kasumin (antibiotic) showed antifungal activity against T. simii in preliminary screening. KOH 0.5% and Formalin 0.5% did not show any antifungal activity against the test dermatophytes. On further study the M.I.C. and M.L.C. of Thiabendarole as fungistatic and fungicidal was 0.312 and 1.25 mg/ml respectively. Similarly in case of Sulfenimide the fungicidal action was present at 0.95% mg/ml.
S K Misra
Source of Support: None, Conflict of Interest: None