| SHORT COMMUNICATION
|Year : 1977 | Volume
| Issue : 1 | Page : 21-23
Long term suppression of gastric acid secretion by diamox in dogs
PS Shetty, P Zachariah
Administration of diamox results in reduction in volume and acid content of histamine-induced gastric secretion in anaesthetised dogs. The effects of inhibition of the enzyme carbonic anhydrase in actively secreting gastric mucosa are not only immediate. But prolonged as seen in subsequent follow up studies for 20 weeks which shows a decrease in acid secreting capacity of stomach in response to histamine.
P S Shetty
Source of Support: None, Conflict of Interest: None