IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 244 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed942    
    Printed66    
    Emailed0    
    PDF Downloaded100    
    Comments [Add]    

Recommend this journal

 

 REVIEW ARTICLE
Year : 1975  |  Volume : 7  |  Issue : 4  |  Page : 47-50

Presenting papers: methods and forms



Correspondence Address:
P C Dandiya


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

The role of 5-hydroxytryptamine (5HT) in hexobarbitone hypnosis has been investigated in albino rats and mice, by employing drugs, with well documented effects on 5HT turnover in brain and noting their interactions with hexobarbitone. 5HT synthesis inhibitor. p-chlorophenylalanine, end methysergide, a specific tryptaminargic receptor antagonist, inhibited hexobarbitone hypnosis and nialamide induced potentiation of hexobarbitone in rats but not in mice. The 5HT precursor, 5HTP, potentiated hexobarbitone action Only in rats and this potentiation was blocked by methysergide. The results indicate that hexobarbitone induced sleep in rats is 5HT mediated, while the same is not true in mice.






[PDF]*


        
Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer
Online since 20th July '04
Published by Wolters Kluwer - Medknow